Preimplantation Genetic Testing (PGT) Malaysia | IVF Genetic Screening | Cytogenomix
Preimplantation Genetic Testing

PGT

Advanced genetic screening of embryos to improve IVF success rates and support healthy pregnancies

>99% Accuracy 7-10 Days TAT All PGT Types

What is Preimplantation Genetic Testing?

PGT is a state-of-the-art genetic testing procedure performed on embryos during IVF to identify genetic abnormalities before implantation.

1

Embryo Biopsy

A few cells are safely removed from the embryo at the blastocyst stage (5-7 days after fertilisation).

2

Genetic Analysis

Cells are analysed using advanced genomic technologies to detect chromosomal abnormalities and genetic mutations.

3

Embryo Selection

Based on genetic results, embryos with the highest chance of leading to a healthy pregnancy are selected for transfer.

Types of PGT We Offer

Comprehensive testing solutions tailored to your specific needs

PGT-A Aneuploidy Screening

Detects chromosomal number abnormalities (aneuploidies) such as Down syndrome, Turner syndrome, and others.

  • Reduces miscarriage risk
  • Improves implantation rates
  • Increases live birth rates
Recommended for:

Advanced maternal age (≥35), recurrent pregnancy loss, multiple IVF failures

PGT-A+ Enhanced Aneuploidy Screening

PGT-A+ is our advanced, enhanced version providing additional layers of analysis including:

  • Comprehensive Aneuploidy Screening
  • Detects Triploidies
  • Screens for Uniparental Disomy
Recommended for:

Advanced maternal age, recurrent pregnancy loss, multiple IVF failures

PGT-M Monogenic Disorders

Screens for specific inherited single-gene disorders such as cystic fibrosis, sickle cell anemia, and Huntington's disease.

  • Prevents transmission of genetic diseases
  • Family-specific test design
  • Comprehensive mutation analysis
Recommended for:

Couples with known genetic disorders, family history of hereditary conditions

PGT-SR Structural Rearrangements

Identifies embryos with balanced or unbalanced chromosomal structural rearrangements (translocations, inversions).

  • Detects translocation carrier status
  • Reduces risk of unbalanced embryos
  • Prevents chromosomal disorders
Recommended for:

Known chromosomal rearrangement carriers, recurrent miscarriage due to chromosomal issues

PGT-HLA HLA Matching

Specialised procedure that allows selection of embryos that are both genetically healthy and HLA-compatible with an existing sibling.

  • Complete HLA typing of affected child and parents
  • Simultaneous testing for genetic disorders
  • HLA compatibility matching
Recommended for:

Families requiring HLA-matched, genetically normal embryos

Molecular PN Check Pronuclear Stage Assessment

Cutting-edge genetic assessment performed at the earliest stage of embryonic development before the first cell division.

  • Genetic evaluation at Day 1
  • Earlier clinical decisions
  • High correlation with blastocyst development
Recommended for:

0 PN, 1PN or PN3 embryos

Benefits of PGT

How genetic testing enhances your IVF journey

Higher Success Rates

Selecting genetically normal embryos increases implantation rates by up to 70% and reduces time to pregnancy.

Reduced Miscarriage Risk

Chromosomal abnormalities cause 60-70% of miscarriages. PGT-A reduces this risk by selecting chromosomally normal embryos.

Single Embryo Transfer

With confidence in embryo viability, single embryo transfer becomes safer, reducing risks of multiple pregnancies.

Prevention of Genetic Disorders

PGT-M allows families with hereditary conditions to have biological children free from specific genetic diseases.

Who Should Consider PGT?

PGT may be recommended for couples facing specific challenges in their fertility journey:

  • Advanced Maternal Age (35 years or older)
  • Recurrent Pregnancy Loss (two or more miscarriages)
  • Previous IVF Failures (multiple unsuccessful cycles)
  • Known Genetic Conditions (family history of genetic disorders)
  • Chromosomal Rearrangements (balanced translocation carriers)
  • Severe Male Factor Infertility
Happy family considering PGT

Our Advanced PGT Technology

Utilizing cutting-edge genomic platforms for accurate results

Next-Generation Sequencing (NGS)

High-resolution comprehensive chromosome screening with >99% accuracy for aneuploidy detection.

Karyomapping

Advanced SNP-based technology for PGT-M that doesn't require family-specific test development.

CMA Technology

Chromosomal microarray analysis for detecting submicroscopic deletions and duplications.

Turnaround Time: 7-10 days for PGT-A, 2-4 weeks for PGT-M (including test design)

Accuracy: >99% for chromosome-level abnormalities, >98% for single-gene disorders

Frequently Asked Questions

Common questions about Preimplantation Genetic Testing

Is PGT safe for embryos?

Yes, embryo biopsy at the blastocyst stage is a well-established procedure with minimal risk. Studies show no increased risk of birth defects or developmental issues in babies born from PGT-tested embryos.

How accurate is PGT?

PGT-A has >99% accuracy for detecting chromosomal abnormalities. PGT-M accuracy is >98% for single-gene disorders. All positive results are confirmed with prenatal testing.

Does PGT guarantee a pregnancy?

While PGT significantly improves success rates, it doesn't guarantee pregnancy. Other factors like uterine receptivity and embryo quality also play important roles.

Can PGT test for all genetic conditions?

PGT-M can test for any single-gene disorder where the genetic mutation is known. PGT-A screens for chromosomal abnormalities but not single-gene disorders unless specifically tested.

Start Your Journey with Confidence

Our team of board-certified genetic counselors and reproductive specialists are here to guide you through every step of the PGT process.

All consultations include a review of your medical history and personalized testing recommendations.

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