Test Code: ONC007
Microsatellite Instability Testing (MSI)
Oncogenetics
Microsatellite Instability (MSI) Testing is a molecular assay used to detect defects in the DNA mismatch repair (MMR) system, a key pathway responsible for correcting errors during DNA replication. Tumours with impaired MMR function accumulate length variations in short repetitive DNA sequences known as microsatellites, resulting in microsatellite instability (MSI).
MSI testing is an essential tool in the evaluation of colorectal, endometrial, gastric, and other solid tumours, and plays a critical role in identifying patients who may benefit from immunotherapy and those who may have Lynch syndrome, an inherited cancer predisposition condition.
MSI testing is an essential tool in the evaluation of colorectal, endometrial, gastric, and other solid tumours, and plays a critical role in identifying patients who may benefit from immunotherapy and those who may have Lynch syndrome, an inherited cancer predisposition condition.
Sample Type
Blood in EDTA; Bone marrow (Na Heparin Tube)
Turnaround Time
10 Days days
Courier Requirements
Ship overnight at room temperature to receive next day. Maintain specimen at room temperature.
Pricing
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Methodology
Capillary Electrophoresis
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